Multiple sclerosis (MS) is a chronic autoimmune and neurodegenerative disease of the central nervous system (CNS), characterized by axonal degeneration and myelin destruction. Various biological models, such as cuprizone intoxication in rodents, are used to simulate the clinical manifestations of MS. This model induces apoptosis of oligodendrocytes, leading to demyelination...
Parkinson's disease (PD) is characterized by a progressive deficit in motor function as a result of the loss of dopaminergic neurons in the substantia nigra. A small percentage of the PD incidence presents a hereditary component, but most cases are sporadic or associated with some chemical and/or environmental factor. 1-...